Thursday, October 24, 2013

iSatori Bio-Gro is "fertilizer for your muscles."

Bio-Gro's introduction to the sports nutrition market sets the stage to change everything you thought you knew about protein use and protein synthesis and its role in your ability to develop muscle.

What is Bio-Gro™?Bio-Gro 5

Bio-Gro is a true "game-changer" from iSatori. The first to introduce a new breed of designer supplementation called Bio-Active Peptides. You can think of Bio-Gro as "fertilizer for your muscles."

How does Bio-Gro work?

iSatori has custom engineered and patented the first and most technically advanced, low molecular weight, micro-concentrated form of Bio-Active Peptides (BAP's) found only in Bio-Gro. Designed to provide a supra-physiological effect that, once consumed, signals the body to amplify its natural protein synthesis process, helping you develop lean muscle and recover faster from intense workouts.

What are Bio-Active Peptides?

Bio-Gro 1The engineered Bio-Active Peptides (or BAP's) found only in Bio-Gro use a patented manufacturing method, whereby cleaved protein fragments are extracted from the highest grade bovine colostrums, which are then centrifugated and micro-concentrated to form a low molecular weight, highly bioavailable powder, yielding an exact concentration of bioactive:

  • Proline-Rich Peptides (PRP's)

  • Growth Factors (IgF, TGF beta-2, EGF, PDGF)

  • Immunoglobulins (IgG, IgA)1,2,5,10

  • Lactoferrin

  • Fibroblast-GF11,16,30

  • Why should I use Bio-Gro?

    There are five reasons you should use Bio-Gro:

    1. More concentrated. A more concentrated form of Bio-Active Peptides means less out-of-pocket expense for you, compared to regular protein powders. That is because one small scoop (1.5 grams) of Bio-Gro contains the equivalent bio-actives as 25 grams of whey protein concentrate. That makes Bio-Gro nearly half the cost, on a serving-per-serving basis, of regular whey protein powders.

    Bio-Gro 2

    2. More convenient. Unlike bulky tablets and flavored powders, Bio-Gro is an unflavored powder in its raw form that is virtually tasteless. Though it doesn't mix well in plain water, it does mix easily into almost everything else-from your protein shake to pre-workout to amino drink, and even in soft foods like yogurt, cereal, or oatmeal, and more.

    3. More scientific research. There are over 32 published clinical studies that back up the demonstrated benefits of the primary ingredient in Bio-Gro. And more importantly, these studies were conducted mostly on well-trained athletes, participants who traditionally show less positive effects compared to untrained individuals.

    4. More expert opinions. There hasn't been a supplement we can think of, to date, that has had more PhD-sports nutrition experts who independently support and validate the science and effects supporting the primary ingredient in Bio-Gro. Including such highly reputable names as Chris Lockwood, PhD; Jeffrey Stout, PhD; Jay Hoffman, PhD; and David Sandler, ABD-PhD.

    5. Highest quality and banned-substance tested. Because iSatori controls the domestic source of our ingredient and has engineered the first micro-concentrated, low molecular weight Bio-Active Peptides found in Bio-Gro, you can trust and count on every batch being of the highest quality and consistency; and what's more, each batch is tested and certified free of any banned substances (via Informed Choice™ ), and is GRAS certified, HALAL, Kosher, and produced in a certified GMP (good manufacturing practice) facility right here in the USA.

    Who should use Bio-Gro?

    Bio-Gro should be used by anyone who is interested in developing or maintaining more lean body mass1-3,5,17,18, 20-24,26-29,33,36-39 and enhancing recovery from exercise or sport.4,6,9,15,35 This would include bodybuilders, fitness, figure, or physique competitors; and athletes competing in any sport, whether collegiate, professional, or recreational. Or, anyone who finds it difficult (or too costly) to consume higher amounts of protein in a day and would rather rely on a more concentrated form of the bio-actives the body will use to amplify protein synthesis.

    Can women use Bio-Gro?

    Absolutely! Many athletic women already do. Because Bio-Gro contains almost zero calories, zero fat, and zero sugars, it is perfect for dieters or women who are calorie- or carb-conscience yet want the bioactive benefits of protein to help develop and maintain lean body tissue.1-3,5,17,18, 20-24,26-29,33,36-39 And Bio-Gro requires only one tiny scoop (1.5 grams) compared to a large-sized protein shake (25 grams or more), that can leave your stomach feeling full of gas and bloated. What's more, Bio-Gro is derived from a natural source and is safe for anyone to consume.

    Bio-Gro 3

    How do I use Bio-Gro?

    Bio-Gro is an unflavored powder that's easy to use. Simply mix one scoop (1.5 grams), two times a day, in liquid (such as a protein shake, pre-workout, or amino drink, etc.) and thoroughly agitate or blend. Although clumping is likely if stirred in plain water, you can also mix Bio-Gro into your favorite soft foods like yogurt, cereal, oatmeal, etc. Bio-Gro can be taken with or without food. For optimal results, follow the bodyweight dosage chart

    Bio-Gro 4

    What does Bio-Gro taste like?

    Bio-Gro is virtually tasteless and can be mixed in just about any drink (other than plain water) or soft food and taken with or without food.

    What can I expect from using it?

    Bio-Gro was designed to augment an important physiological function to a greater capacity than it can on its own (no matter how much protein or aminos you consume). It does this by assisting your body to signal and accelerate the rate at which it processes the building and re-building of muscle tissue, called protein synthesis. 1-3,5,17,18, 20-24,26-29,33,36-39 By doing so, you can develop lean body mass at a faster rate, more efficiently. Additionally, and equally important, you should notice a reduction in recovery time after bouts of intense exercise or weight training. 4,6,9,15,35 Therefore, Bio-Gro should be used daily and consistently over time, just as you would food or other sources of protein. And better yet, so far as the anecdotal reports suggests, the more you use, the better and more profound its effects:

  • Step 1 (Consume Bio-Gro)

  • Step 2 (Train hard)

  • Step 3 (consume adequate protein)

  • Step 4 develop lean muscle and reduce recovery time)

  • Are there any scientific studies to support Bio-Gro?

    Yes. To date, there are over 32 clinical studies, conducted from 1990-2011, which demonstrate the positive effects of the primary ingredient inside Bio-Gro, including improvements in lean body mass, 1-3,5,17,18, 20-24,26-29,33,36-39 performance,7,10,12,19,25,34 recovery, 4,6,9,15,35 strength,8 and immune function,13,14 and more are currently underway.

    Are there any banned substances in Bio-Gro?

    No. Bio-Gro's primary ingredient is sourced locally, produced in GMP-certified facility, and every batch is tested and certified free of any banned substance. These tests are available upon request and performed by Informed Choice™ and/or HFL Sport Science. Bio-Gro complies with all collegiate and athletic organizations' nutritional requirements.

    What are some reports of those who have used Bio-Gro?

    During our four years of diligent research and development, there were several hundred "beta-test" participants who experimented with Bio-Gro. Here is a small sample of what they had to say:

    "Bio-Gro is now part of our strict regimen of supplementation for all of our elite athletes."

    "When we undertook the task of evaluating Bio-Gro, we were skeptical because our athletes are of a heightened level of success so any slight percentage increase in performance would prove to be significant and incredibly useful. Thank goodness we were right! Not only did we see an improvement in our [athlete's] performance, we also saw reduced recovery time using a natural product that is free of any banned substances. We were thrilled! We have, to date, trained 135 elite athletes on Bio-Gro, including several Olympic hopefuls and over 134 All-Americans at the high school and collegiate level. Bio-Gro is now part of our strict regimen of supplementation for all of our elite athletes."

    --Jude Massillon, Owner, Sports Performance Group, Rockville Centre, NY

    "I've gained a solid inch on my arms in one month!"

    "I've always been a naturally muscular guy, and must admit, I'm very skeptical of most supplements. In fact, other than amino acids and protein, I don't heavily rely on any other supplements. Then we started testing Bio-Gro, and because I am the Director of Science of Education for iSatori, I got the benefit of using it well before anyone else. By monitoring my progress closely, I discovered Bio-Gro has helped me put a solid inch of muscle on my arms, during the first month I used it. And, I can tell how it markedly helps me recover much faster after workouts. I can say, with absolutely certainty, Bio-Gro is not only in a class of its own but it will set the stage in Bio-Active Peptides and is here to stay for many, many years to come."

    --D. Sandler, ABD-PhD, CSCS; Director of Science & Education, iSatori

    "Everything I eat seems to turn to muscle!"

    "I'm what you would call your typical ‘hard-gainer.' Even though I am no stranger to the gym and lifting weights, all of my life, I have had the most difficult time gaining weight, let alone muscle mass. No matter what I ate, or how much protein I consumed, I just have never been able to pack on any respectable amount of bodyweight and keep it on.

    "That all changed when I was introduced to Bio-Gro during their beta-test phase of development. I happen to work out at a gym in Colorado, where they were soliciting for participants in their pilot studies. I volunteered, and man, am I glad I did. Over the last three months of using Bio-Gro, two sometimes three times daily, I have gained over 15 pounds of muscle mass. That might not sound like a lot, but measured by high-spectrum calipers and a body-dunk procedure, it was verified that every single ounce of the weight I gained was solid muscle mass. Not an ounce of fat. And I ate of lot of pretty much everything.

    "It just seemed like everything I ate turned to muscle. I have to say that without a reason of doubt, Bio-Gro was the answer to unlocking my natural ability to put on muscle mass as a true hard-gainer. This stuff is the real deal, and like they told me when they gave it to me, it's real ‘game-changer.'"

    --Scott Charles Bell, Construction Foreman (Age 41)

    "You might think this is just for men, but you're dead wrong!"

    "I've been involved in women's fitness and figure competitions for over 10 years, and now I work as a pharmaceutical representative, as well as personal train over 25 clients in the Dallas area. I understand, for me and my clients, how important it is as a competitor, or someone trying to alter their body composition, to improve lean body mass favorably compared to fat mass, and Bio-Gro did just that.

    "When I was introduced to Bio-Gro, after one brief explanation, I immediately realized its benefits. What drew me to Bio-Gro was the convenience, because I don't always like consuming a giant protein shake, especially when I'm not hungry, and it normally leaves me with gas or bloating, which I hate; and with Bio-Gro, you only have to take one tiny scoop; what's more, I liked that Bio-Gro didn't contain any calories, sugar, or fat, which is great when you are dieting or trying to be mindful of your calories or sugar; and best of all, I was impressed by the amount of science behind it. I use Bio-Gro every day, twice a day, and recommend that all of my clients use it too."

    --Krista Gibson, Pharmaceutical Sales Rep, & Certified Personal Trainer (Age 34)

    If I have more questions, who can I contact?

    If you have any questions, whatsoever, about Bio-Gro or your nutrition or training in general, please don't hesitate to contact one of our expert advisors directly at iSatori, by calling 1-866-688-7679 or emailing

    Scientific References:

    1 [IgF-1 relation to protein synthesis and muscle growth] Adams GR, Haddad F. "The relationships among IGF-1, DNA content, and protein accumulation during skeletal muscle hypertrophy," J Appl Physiol, 1996; 81:2509–2516.

    2 [IgF-1 relation to protein synthesis and muscle growth] Adams GR, McCue SA, "Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats," J Appl Physiol, 1998; 84:1716–1722.

    3 [LBM] Antonio, J, Sanders, MS, and Darin, VG, "The effects of bovine colostrum supplementation on body composition and exercise performance in active men and women," Nutrition, 2001, 243-247.

    4 [Recovery] Appukutty, et al., "Modulation of interferon gamma response through orally administered bovine colostrum in active adolescent boys," Biomedical Research, 2011, 18-22.

    5 [IgF-1 relation to protein synthesis and muscle growth] Bolster, DR, et al., "Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin-like growth factors, amino acid- and exercise-induced signaling," Proc Nutr Soc, 2004; 63:351–356.

    6 [Recovery] Brinkworth, GD, et al., "Concentrated bovine colostrum protein supplementation reduces the incidence of self-reported symptoms of upper respiratory tract infection in adult males," European Journal of Nutrition, 2003, 228-232.

    7 [Performance] Brinkworth, GD, et al., "Oral bovine colostrum supplementation enhances buffer capacity but not rowing performance in elite female rowers," International Journal of Sport Nutrition and Exercise Metabolism, 2002, 349-365.

    8 [Strength] Brinkworth, GD, et al., "Effect of bovine colostrum supplementation on the composition of resistance trained and untrained limbs in health young men," European Journal Applied Physiology, 2004, 53-60.

    9 [Recovery] Buckley, JD, et al., "Bovine colostrum supplementation during endurance running training improves recovery, but not performance," Journal of Science and Medicine in Sport, 2002, 65-79.

    10 [Perf, IgF-1] Buckley, JD, Brinkworth, GD, and Abbott, MJ, "Effect of bovine colostrum on anaerobic exercise performance and plasma insulin-like growth factor 1,"Journal of Sports Sciences, 2003, 577-588.

    11 [profile] Christiansen, Scott, et al., "Chemical composition and nutrient profile of low molecular weight fraction of bovine colostrums," Int Dairy Journal, 2010, September 20.8.630-636.

    12 [Performance] Coombes, JS, et al., "Dose effects of oral bovine colostrum on physical work capacity in cyclists," Medicine and Science in Sports & Exercise, 2002, 1184-1188.

    13 [Immune] Crooks, CV, et al., "The effect of bovine colostrum supplementation on salivary IgA in distance runners," Int J Sport Nutr Exerc Metab, 2004, 47-64.

    14 [Immune] Crooks, C, et al., "Effect of bovine colostrum supplementation on respiratory tract mucosal defenses in swimmers," International Journal of Sport Nutrition and Exercise Metabolism, 2010, 224-235.

    15 [Recovery] Davison, G, et al., "Bovine colostrum supplementation attenuates the decrease of salivary lysozyme and enhances the recovery of neutrophil function after prolonged exercise," British Journal of Nutrition, 2010, 1425-1432.

    16 [Bioactive fractions] Doillon, Charles J, et al., "Modulatory effect of a complex fraction derived from colostrums on fibroblast contractibility and consequence on repair tissue," Int Wound Journal, 2011: 8:280-290.

    17 [IgF-1 relation to protein synthesis and muscle growth] Fryburg, DA, et al., "Insulin and insulin-like growth factor-I enhance human skeletal muscle protein anabolism during hyperaminoacidemia by different mechanisms," J Clin Invest, 1995; 96:1722–1729.

    18 [IgF-1 relation to protein synthesis and muscle growth] Gostelli-Peter, M, et al., "Expression and regulation of insulin-like growth factor I (IGF-I) and IGF binding protein messenger ribonucleic acid levels in tissues of hypophysectomized rats infused with IGF-I and growth hormone," Endocrinology, 1994; 135:2558–2567.

    19 [Performance] Hofman, Z, et al., "The effect of bovine colostrum supplementation on exercise performance in elite field hockey players," Int J Sport Nutri Exerc Metab, 2002, 461-469.

    20 [LBM] Kerksick, CM, et al., "Impact of differing protein sources and a creatine containing nutritional formula after 12 weeks of resistance training," Nutrition, 2007, 647-656.

    21 [LBM] Kerksick, CM, et al., "Effects of bovine colostrum supplementation on training adaptations II: performance," 85th Annual Experimental Biology, 2001 (p. 15:LB58). Orlando, Fl: FASEB J.

    22 [LBM] Kreider, R, et al., "Effects of bovine colostrum supplementation on training adaptations I: body composition," 85th Annual Experimental Biology, 2001 (p. 15:LB58). Orlando, FL: FASEB J.

    23 [IgF-1 relation to protein synthesis and muscle growth] Le Roith D, et al., "The somatomedin hypothesis: 2001," Endocr Rev, 2001;22:53–74.

    24 [IgF-1 relation to protein synthesis and muscle growth] Liu, JP, Baker J, et al., "Mice carrying null mutations of the genes encoding insulin-like growth factor I (IGF-1) and type 1 IGF receptor (IGF1R) Cell," 1993;75:59–72.

    25 [Performance] Marshall-Gradisnik, SM, et al., "Psychological improvements in healthy males after eight weeks of concentrated bovine colostrum supplementation," 2003 Foods for Life Conference, Incorporating International Dairy Federation (p. 197), 2003, Melbourne: Australian Journal of Dairy Technology.

    26 [IgF-1 relation to protein synthesis and muscle growth] Mauras, N, et al., "Are the metabolic effects of GH and IGF-I separable," Growth Horm IGF Res, 2005; 15:19–27.

    27 [IgF] Mero, A, et al., "IGF-I, IgA, and IgG responses to bovine colostrum supplementation during training," J Appl Physiol, 2003, 732-739.

    28 [Protein synthesis] Mero, A, et al., "Effects of bovine colostrum supplementation on serum IGF-1, IgG, hormone, and saliva IgA during training," J Appl Physiol, 1997, 1144-1151.

    29 [IgF] Mero, A., et al., "Protein metabolism and strength performance after bovine colostrum supplementation," Amino Acids, 2005, 327-335.

    30 Nissen, Asger, et al., "In-depth analysis of low abundant proteins in bovine colostrums using different fraction techniques," Proteomics 2012; 12, 2866-2878.

    31 [Power] O'Leary, L, et al., "Assessment of anaerobic performance in healthy males after an eight week concentrated bovine colostrum supplementation," Australian Conference of Science and Medicine in Sport and Third National Sports Injury Prevention Conference (p. 38), 2003, Dicson: Australia.

    32 Playford, R., Study 1: "Effect of colostral preparations on cell proliferation." Study 2: "Effect of colostral preparations on cell migration." Non-published. Hammersmith Hospital. London, UK.

    33 [IgF-1 relation to protein synthesis and muscle growth] Rennie, MJ, "Claims for the anabolic effects of growth hormone: a case of the emperor's new clothes," Br J Sports Med, 2003; 37:100–105.

    34 [Performance] Shing, CM, et al., "The influence of bovine colostrum supplementation on exercise performance in highly trained cyclists," British Journal Sports Medicine, 2006, 797-801.

    35 [Recovery] Shing, CM, et al., "Effects of bovine colostrum supplementation on immune variables in highly trained cyclists," Journal of Applied Physiology, 2007, 1113-1122.

    36 [IgF-1 relation to protein synthesis and muscle growth] Velloso, CP, et al., "Regulation of muscle mass by growth hormone and IGF-I," Br J Pharmacol, 2008 June; 154(3): 557–568.

    37 [IgF-1 relation to protein synthesis and muscle growth] Walenkamp, MJ, et al., "Genetic disorders in the GH IGF-I axis in mouse and man," Eur J Endocrinol, 2007; 157:S15–S26.

    38 [IgF-1 relation to protein synthesis and muscle growth] Yarasheski, KE, et al., "Effect of growth hormone and resistance exercise on muscle growth in young men," Am J Physiol, 1992; 262:E261–E267.

    39 [IgF-1 relation to protein synthesis and muscle growth] Yarasheski, KE, et al., "Effect of growth hormone and resistance exercise on muscle growth and strength in older men," Am J Physiol, 1995; 268:E268–E276.