Why are PDE5 inhibitors of use to bodybuilders? The same reason they are of use in the bedroom. Although the latter is more important.....there's nothing like a good pump. (no pun intended)
Here are three ingredients you should look for for bigger pumps.
Horny Goat Weed (Epimedium or Yin Yang Huo) 500mg to 4 grams (divided doses)
Xanthoparmelia Scarbrosa The typical dose is 1000-1500mg one to two hours prior to sexual activity).
Cnidium Monnieri Take 30-50 mg of cnidium monnier when you take arginine.
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According to Wikipedia:
"Epimedium, also known as barrenwort, bishop's hat, fairy wings, horny goat weed, or yin yang huo, is a genus of flowering plants in the family Berberidaceae"
"A phosphodiesterase type 5 inhibitor, often shortened to PDE5 inhibitor, is a drug used to block the degradative action of phosphodiesterase type 5 on cyclic GMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of the penis. These drugs are used in the treatment of erectile dysfunction, and were the first effective oral treatment available for the condition. Because PDE5 is also present in the arterial wall smooth muscle within the lungs, PDE5 inhibitors have also been explored for the treatment of pulmonary hypertension, a disease in which blood vessels in the lungs become overloaded with fluid, usually as a result of failure of the left ventricle of the heart."
All that to say that PDE5 inhibitors allow nitric oxide to stick around. That is a good thing in the gym and the bedroom.
Men are often looking for natural alternatives to PDE5 inhibitors Viagra (sildenafil ), made by Pfizer, Eli Lilly’s Cialis (tadalafil) and GlaxoSmithKline’s Levitra (vardenafil).
The most popular of these is Horny Goat Weed and effective dosages appear to be between 500mg to 4 grams per day depending on your specific needs.
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Sources:
Phosphodiesterase Inhibitors PDE5 inhibitors by Ray Sahelian, M.D.
Stoppani, Jim. "Turbo boosters: 11 supplements that get your blood flowing and the testosterone pumping for stronger workouts and bigger gains in size and strength." Joe Weider's Muscle & Fitness. 67.6 (June 2006): 196(4).
Reference:
Lazarou J, Pomeranz BH, Corey PN: “Incidence of adverse drug reactions in hospitalized patients.” JAMA 1998;279:1200.
Nicolosi A, Moreira ED Jr, Shirai M, Bin Mohd Tambi MI, Glasser DB.: Epidemiology of erectile dysfunction in four countries: cross-national study of the prevalence and correlates of erectile dysfunction. Urology 2003 Jan;61(1):201-6
Parazzini F, Menchini Fabris F, Bortolotti A, Calabro A, Chatenoud L, Colli E., Landoni M, Lavezzari M,, Turchi P, Sessa A, Mirone V.: Frequency and determinants of erectile dysfunction in Italy Eur Urol 2000 Jan;37(1): 43-9
BJU Int 2006;98:1255-1258.
SOURCE: Bacon, C. Annals of Internal Medicine, August 2003; vol 139: pp 161-168.
Campbell, T. Colin (2006). The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health. Benbella Books. ISBN 1-932100-38-5
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