Thursday, November 27, 2014

SuppVersity - Nutrition and Exercise Science for Everyone: SuppVersity Science Round-Up Seconds: All About DH...

SuppVersity - Nutrition and Exercise Science for Everyone: SuppVersity Science Round-Up Seconds: All About DH...: A lack of libido appears - if at all - treatable w/ DHEA only in peri-menopausal women (Maggi. 2013; Pucchino. 2013); there are however a ...
  • men and women with hyperthyroidism - the increased thyroid activity "burns" through all adrenal hormones, so that backup (of both DHEA and cortisol) can become necessary (Agbaht. 2013)
  • patients on glucocorticoids (e.g. for inflammatory or immune
    diseases) - cortisol and synthetic glucocorticoids suppress DHEA
    production - it's thus logical that backfilling the missing hormones can
  • people on severe chronic stress - the military, for example
    has conducted a handful of interesting studies; two of the most recent
    studies were conducted by Taylor et al. (2012) and Taylor (2013) - the
    researchers report neuroprotective and anabolic effects with 50mg/day
    (classroom phase) and 75mg/day (training in the field), respectively
  • people using non-aromatizing steroids - DHEA can provide a precursor for a baseline estrogen level even on suppressive non-aromatizing drugs (listen to the show for more details)
  • patients suffering from lupus erythematosus ["syndrome like" =
    very unspecific autoimmune disease usually with sever joint pain and
    arthritis, ca. 5 mio people world-wide suffer; every year 100,000 new
    cases in the US / constantly increasing (Buvat. 2003); honestly I
    suspect this leaves more cortisol to get the inflammation under control,
    but hey what do I know; usually women, often African American or
    latino] proven benefit from 200mg/day
  • women with diminished ovarian reserve - while the latest
    review says the evidence was not there, I consider the results of a
    study by Gleicher (2009), alone, worth giving it a try: The researchers
    observed a restoration of the rate of miscarriages to normal levels in
    the 73 cases they evaluated – that’s a reduction of -51% risk of having a
    miscarriage and direct effect on the occurrence of genetic disorders
    like "Trisomy 21" [= down syndrome] in women with diminished
    ovarian reserve (Gleicher. 2010) - still: don't even think about messing
    with your hormones, when you are healthy and wand to become pregnant!