Tuesday, January 27, 2015

SuppVersity - Nutrition and Exercise Science for Everyone: Whey Beyond Brawn: 10+ Things You Probably Didn't ...

SuppVersity - Nutrition and Exercise Science for Everyone: Whey Beyond Brawn: 10+ Things You Probably Didn't ...: If you've got brawn and brain you will realize that whey is much more than a potent muscle builder. As a SuppVersity reader you are ...

  • b-lactoglobulin binds retinol (vitamin A) and promotes uptake
    of retinol via gut; by a similar mechanism it may also facilitate the
    uptake of long-chain fatty acids
  • a-lactoalbumin kills tumour cells (in vitro) and exerts
    anti-bacterial effects in the upper respiratory systems; it has also
    been shown to have protective effects on gastric mucosa.
  • Table 1: Content
    of minor bioactive proteins in whey concentrates (levels are probably
    lower in iso- and hydrolysates | values from Smithers. 2008) and the
    lactalbumin fractions. Since the major proteins in whey (not listed
    here) can form bonds with albumin (Havea. 2001), whey is another case,
    where an increase in processing may lead to a decrease in beneficial
    biological activity.
    lactoferrin regulates the absorption of iron via gut; it will
    inhibit the growth of various bacteria and regulates immunological
    response of immunocomponent cells
  • serum albumin binds and carries fatty acids and bile pigment
  • immuno-globulin G involves with bactericidal (anti-bacterial)
    effects with complements and prevents bacteria from adhering to
    tissues; neutralizes toxins and viruses
  • immuno-globulin A inhibits growth of various bacteria by
    condensing them; prevents bacteria from adhering to the surface of
    mucosa; neutralizes toxins produced by viruses and bacteria.
  • immuno-globulin M has the same effects as IgG, but its bioactivity is stronger
  • lactoperoxidase catalyzes the reaction of producing cyanogen
    ion with strong bactericidal power from cyanic ion and hydrogen peroxide
    in the body
  • lysozyme kills bacteria by destroying cell walls


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    the exercise-induced heat shock protein (HSP70) response in rats." Food
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  • FitzGerald, Richard J., Brian A. Murray, and Daniel J. Walsh.
    "Hypotensive peptides from milk proteins." The Journal of Nutrition
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  • Hall, W. L., et al. "Casein and whey exert different effects on
    plasma amino acid profiles, gastrointestinal hormone secretion and
    appetite." British Journal of Nutrition 89.02 (2003): 239-248. 
  • Havea, Palatasa, Harjinder Singh, and Lawrence K. Creamer.
    "Characterization of heat-induced aggregates of β-lactoglobulin,
    α-lactalbumin and bovine serum albumin in a whey protein concentrate
    environment." Journal of Dairy Research 68.03 (2001): 483-497.
  • Ikeda, Masanori, et al. "Lactoferrin markedly inhibits hepatitis C
    virus infection in cultured human hepatocytes." Biochemical and
    biophysical research communications 245.2 (1998): 549-553. 
  • Markus, C. Rob, Berend Olivier, and Edward HF de Haan. "Whey protein
    rich in α-lactalbumin increases the ratio of plasma tryptophan to the
    sum of the other large neutral amino acids and improves cognitive
    performance in stress-vulnerable subjects." The American journal of
    clinical nutrition 75.6 (2002): 1051-1056.
  • Marshall, Keri N. D. "Therapeutic applications of whey protein." Alternative Medicine Review 9.2 (2004): 136-156.
  • Pal, Sebely, and Vanessa Ellis. "The chronic effects of whey
    proteins on blood pressure, vascular function, and inflammatory markers
    in overweight individuals." Obesity 18.7 (2010a): 1354-1359.
  • Pal, Sebely, Vanessa Ellis, and Satvinder Dhaliwal. "Effects of whey
    protein isolate on body composition, lipids, insulin and glucose in
    overweight and obese individuals." British journal of nutrition 104.05
    (2010b): 716-723.
  • Pal, Sebely, Vanessa Ellis, and Suleen Ho. "Acute effects of whey
    protein isolate on cardiovascular risk factors in overweight,
    post-menopausal women." Atherosclerosis 212.1 (2010c): 339-344. 
  • Pal, Sebely, and Simone Radavelli‐Bagatini. "The effects of whey
    protein on cardiometabolic risk factors." Obesity Reviews 14.4 (2013):
  • See D, Mason S, Roshan R. "Increased tumor necrosis factor alpha
    (TNFalpha) and natural killer cell (NK) function using an integrative
    approach in late stage cancers." Immunol Invest 21 (2002):137-153.
  • Smithers, Geoffrey W. "Whey and whey proteins—from ‘gutter-to-gold’." International Dairy Journal 18.7 (2008): 695-704.
  • Tsutsumi, R., and Y. M. Tsutsumi. "Peptides and proteins in whey and
    their benefits for human health." Austin J Nutri Food Sci 1.1 (2014):
  • Watanabe, Akiharu, et al. "Nutritional therapy of chronic hepatitis
    by whey protein (non-heated)." Journal of medicine 31.5-6 (1999):