Bottom line: Whether we are seeing a "muscle full" effect is something
that's difficult to tell. What appears to be certain, though, is that resistance
training allows for a greater uptake of protein synthesis (Tang. 2009; 0.15% /h
in response to resistance training + whey protein). Although the supplements
were somewhat different, I am thus inclined to believe that the absence of
resistance training and the corresponding mTOR-C2 activation in response to
aerobic ( (mTORC1 by supplementation, only) vs. resistance training (mTORC1 by
supplementation, mTORC2 by contraction) is the limiting factor, here (Drummond.
2009).
The latter would imply that the results are not applicable
to resistance training directly. Even if corresponding studies clearly suggest
that there is a limit to the benefits of "evermore" protein with resistance
training, as well, the "limit" may be higher than "just" 23g of mixed dairy
protein + 5g of leucine.Reference:
- Atherton, Philip J., et al. "Muscle full effect after oral protein:
time-dependent concordance and discordance between human muscle protein
synthesis and mTORC1 signaling." The American journal of clinical nutrition 92.5
(2010): 1080-1088. - Drummond, Micah J., et al. "Rapamycin administration in humans blocks the
contraction-induced increase in skeletal muscle protein synthesis." The Journal
of physiology 587.7 (2009): 1535-1546. - Rowlands, David S., et al. "Protein-Leucine Fed Dose Effects on Muscle
Protein Synthesis After Endurance Exercise." Medicine & Science in Sports
& Exercise (2014). - Tang, Jason E., et al. "Ingestion of whey hydrolysate, casein, or soy
protein isolate: effects on mixed muscle protein synthesis at rest and following
resistance exercise in young men." Journal of Applied Physiology 107.3 (2009):
987-992.
