Showing posts with label Berberine. Show all posts
Showing posts with label Berberine. Show all posts

Thursday, November 16, 2017

Carb and Fat Blocker Stack: Orlistat and Berberine


1) Orlistat as directed
2) Berberine with last meal


You still have to eat a sensible diet.  Use myfitnesspal .com to track your calories, macros and weight. Also, start slow. Both Berberine and Orlistat can cause loose bowel movements. A multivitamin is suggested when using Orlistat since it may prevent the absorption of some nutrients.

Always see your doctor before starting a weight loss program or for questions about taking supplements. 




Further Reading:

Berberine - Scientific Review on Usage, Dosage, Side Effects ...

https://examine.com/supplements/berberine/

Berberine is a compound extracted from a variety of herbs. It is supplemented for its anti-diabetic effects, which rival the potency of some pharmaceuticals.

Orlistat - Wikipedia

https://en.wikipedia.org/wiki/Orlistat

Orlistat is a drug designed to treat obesity. It is marketed as a prescription drug under the trade name Xenical by Roche in most countries, and is sold ...
Trade names‎: ‎Xenical, Alli
Pregnancy category‎: ‎AU: ‎B1‎; US: ‎X‎ (Contraind...
Biological half-life‎: ‎1 to 2 hours
Formula‎: ‎C29H53NO5




Well Reviewed White Kidney Bean Based Alternatives to Orlistat




DISCLAIMER

Information found on whey2muscle/helpyougetgains is meant for educational and
informational purposes only, and to motivate you to make your own health care
and dietary decisions based upon your own research and in partnership with your
health care provider. It should not be relied upon to determine dietary changes,
a medical diagnosis or courses of treatment.

Monday, August 28, 2017

Glucose Disposal Agent Performax Slin Max Moves Nutrients into Muscle





SlinMax is definitely not your average muscle builder and is unique in its ability to work with the most anabolic hormone in your body, Insulin. SlinMax works as an insulin mimetic while also boosting insulin production and increasing insulin sensitivity. Insulin is high synergistic with Androgens, Growth Hormone, IGF and other hormones that effect muscle growth and through this synergism SlinMax can have extremely impressive effects on muscle growth, size, vascularity and even weight loss!

Na-R-ALA

is a salt form or R-ALA that drastically increases both stability and absorption and is known for its effects as a nutrient partitioner. Na-R-ALA is not only a very potent anti-oxidant it also is great at lowering blood glucose and increasing muscle glycogen storage through its ability to recruit glucose transporter GLUT-4!

Agmatine Sulfate

is incredibly well known for its ability to increase Nitric Oxide and enhance the ‘pump’ but what most don’t know is that Agmatine can also improve insulin sensitivity and glucose uptake in skeletal muscle tissue. It is believe Agmatine can promote the release of b-endorphin that can remove glucose from the blood and increase its storage in muscle tissue producing muscular fullness and nutrient uptake!

Berberine HCL

is a very exciting compound as there is solid human evidence proving its efficiency and ability to increase glucose disposal. Berberine has the unique effect of increasing AMPK, short for AMP Activated Protein Kinase which regulates insulin and glucose transport. When AMPK is activated glucose can be taken up into muscle cells through GLUT-4 transporter.

Banaba(2% Corosolic Acid)

is synergistic with Berberine with its ability to also increase GLUT-4 translocation and glucose uptake. However Corsolic Acid also may have the unique ability to act as an agonist of the insulin receptor, directly activating the insulin receptor itself. Banaba extract is also included in this product as it seems to contain compounds that may reduce fat cell proliferation thereby allowing SlinMax to have a more direct effect on muscle tissue and reduce the risk of fat gain.

4-hydroxyisoluecine

is a natural constituent of Trigeonella Seed, also known as Fenugreek. Fenugreek is well known for its effects on Testosterone production however it’s also been shown 4-hydroxyisoluecine, almost soley found in Fenugreek, can increase insulin secretion and help reduce blood glucose levels. As well it can help regulate healthy glucose metabolism and increase insulin sensitivity as well as post-meal glucose tolerance!

Black Pepper Extract

is known for its ability to inhibit enzymes that could degrade or breakdown certain compounds. Black Pepper Extract was included to increase bioavailability of co-ingested ingredients and specifically help the proper absorption of ingredients like Berberine, leading to a greater effect and less side effects associated with poor intestinal uptake.



Tuesday, August 22, 2017

Suppversity Excerpt: Berberine Supplements (Names Included) on the US Market Contain More/Less Berberine Than the Label Says

SuppVersity - Nutrition and Exercise Science for Everyone: 9/15 Berberine Supps (Names Included) on the US Ma...: Berberine is a yellow-colored alkaloid compound found in several different plants, including European barberry, goldenseal, goldthread, Or...

Health threat? Isn't that an exaggeration? Well, it depends. For the average consumer, it probably ain't a problem. With the ever-increasing number of studies that show that berberine could be used instead of metformin and/or on top of medical treatments for high blood glucose and/or lipids, some consumers may end with lower/higher levels of glucose or lipids in the blood when they (a) switch from one 500mg product to the other or (b) simply start a new bottle that was produced by the same manufacturer, but contains more/less of the active ingredient (note: I personally was afraid that the deviations from the label may be much larger and am relatively happy with the results, but I guess that's my personal disillusionment).


The last-mentioned possibility that the potency varies not just between products, but also from batch to batch, is also why I wouldn't rely too much on the data from the study at hand.  The next batch of supplement #9, the "best" supplement in this study, of which the authors rightly point out that it was limited "[p]rimarily" by the fact that they "analyzed the berberine content of one individual bottle from each manufacturer" (Funk 2017), may well contain significantly lower amounts of berberine than the one that was tested by Funk et al. for the study at hand. As previously hinted at, this is a general problem with dietary supplements. It's a problem you should know about, and one that disqualifies them as 1:1 replacement for medications, but not one that should make you shy away from supplements altogether, in my humble opinion.




References:

  • Funk, R.S. et al. "Variability in Potency Among Commercial Preparations of Berberine." J Diet Suppl. 2017 Aug 9:1-9. doi: 10.1080/19390211.2017.1347227. [Epub ahead of print]
  • Brown, Paula N., and Mark C. Roman. "Determination of hydrastine and berberine in goldenseal raw materials, extracts, and dietary supplements by high-performance liquid chromatography with UV: Collaborative study." Journal of AOAC International 91.4 (2008): 694-701.
  • Dong, Hui, et al. "Berberine in the treatment of type 2 diabetes mellitus: a systemic review and meta-analysis." Evidence-Based Complementary and Alternative Medicine 2012 (2012).
  • Dong, Hui, et al. "The effects of berberine on blood lipids: a systemic review and meta-analysis of randomized controlled trials." Planta medica 79.06 (2013): 437-446.
  • Edwards, David J., and Emily J. Draper. "Variations in alkaloid content of herbal products containing goldenseal." Journal of the American Pharmacists Association 43.3 (2003): 419-423.
  • Gershwin, M. Eric, et al. "Public safety and dietary supplementation." Annals of the New York Academy of Sciences 1190.1 (2010): 104-117.
  • Sarma, Nandakumara, Gabriel Giancaspro, and Jaap Venema. "Dietary supplements quality analysis tools from the United States Pharmacopeia." Drug testing and analysis 8.3-4 (2016): 418-423.
  • Sun, Yiyi, et al. "A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs." Anti-cancer drugs 20.9 (2009): 757-769.
  • Ye, Minzhong, et al. "Neuropharmacological and pharmacokinetic properties of berberine: a review of recent research." Journal of Pharmacy and Pharmacology 61.7 (2009): 831-837.

Tuesday, May 10, 2016

Supplements to Take Advantage of the Most Anabolic Hormone Insulin

Chromium Picolinate increases muscle cell insulin sensitivity.

Alpha Lipoid Acid (ALA) is an anti-oxidant that increases insulin sensitivity and glucose metabolism.

Cinnamon delays gastric emptying, lowesr blood glucose levels following meals and reduces fasting insulin.

Berberine is an sensitizer that increases the use of the anabolic hormone insulin.

Cyanidin 3-glucoside (C3G) effects insulin signaling, selective insulin sensitivity, glucose and nutrient repartitioning.


Apple Cider Vinegar (ACV) lowers glucose and insulin responses and increases satiety after a bread meal in health.

Ursolic Acid shows promise as a repartitioning agent.

Vanadyl Sulfate helps with uptake of glucose into muscle cells instead of fat cells. 


Monday, August 31, 2015

Product Review and Results of the AgeForce Weight Loss Patch Experiment





Nine weeks (8 actually) I have lost 6 pounds total and 2 inches off of my waist. I am very happy with the results in that I did not diet at all. I wanted to isolate the results from all other external influences.

I experienced no side affects. No loss of sleep or muscle cramps or high water loss. The experiment itself was very interesting in that I still ate horribly but weight came off. 

With more effort I believe the AgeForce patch would cause some significant body re-composition. Definitely worth adding to your current protocol. 

I would like to absolutely thank the folks at AgeForce for the opportunity to test the patch.

A few basic starting measurements as listed below:

Weight: 222 lbs
Body Fat: 41%
Waist Circumference: 44 inches.
Start Date: 7/6/15



Current measurement of progress.






The workout schedule is listed below in the link below.

My August Training - Century Sets - 100 rep workouts

 

I am amended my workout and started a 15-30 minute jog/walk per day cardio workout. Similar to the below link.

5K run: 7-week training schedule for beginners - Mayo Clinic




The Below Information is from the AgeForce Website:

Formula (Per Patch) Upgraded June 2015
  • EGCG 5mg – From green tea extract is the best-researched anti-inflammatory fat loss adjuvant your money can buy. In its purest form it will fire up your fat metabolism and help normalize your glucose levels.
  • Berberine HCL 10mg – A powerful fat-metabolic enhancer that acts similar to the potent diabetes drug metformin. Just like the prescription medication it acts mainly via an enzyme that's called AMPK. AMPK controls the glucose uptake and fatty acid oxidation in your cells and berberine ramps up both of them. Studies have also shown that berberine can reduce the levels of triglycerides and bad LDL cholesterol in your blood, albeit without any of the nasty side effects of prescription drugs with the same effects.
  • 3.5 Diiodothyronine (T2) 1mg – is a downstream metabolite that is a thermogenic activator that promotes the burning of body fat. 3.5 is also the most powerful and effective of the two forms of T2.
  • 7-Keto DHEA 20mg– (7-OXO DHEA) is a naturally occurring metabolite of DHEA that cannot convert to estrogen, testosterone or any downstream sex hormone making it a much safer choice for those wanting the well-known weight loss benefits of DHEA. Clinical trials and peer review studies show that 7-Keto DHEA works as a thermo genic that increases metabolic function and thus causes an increase in energy expenditure. This leads to greater calorie utilization with resulting fat loss. 7-Keto DHEA can also accelerate fat loss is through a reduction of cortisol production which place a roll in the storage of new body fat. So 7-Keto DHEA works two ways, by increasing body fat loss and inhibiting new fat storage.
  • Tyr-Somatostatin 5mg - is an advanced peptide that burns body fat without any of the negative effects of so-called “fat-burners” like caffeine, ephedrine, or guarana, that are used in other over-the-counter weight loss supplements and diet pills. Tyr-Somatostatin does not suppress natural thyroid production.
  • R Alpha Lipoic Acid (RLA) 5mg - is a great antioxidant. It is used in the body to break down carbohydrates, and to make energy. It also restores natural levels of vitamin C and vitamin E.
  • Hoodia 15mg – This is a safe and wonderful appetite suppressant. It doesn’t work when taken orally, but when delivered directly to the bloodstream via our patches, it will suppress appetite and those cravings that make it so hard to eat sensibly.
  • Yohimbine 10mg – Increases lipolysis as shown in multiple studies, especially during and following exercise, thus promoting safe, natural weight loss. Yohimbine is a mild stimulant.
  • Hordenine 4mg – Is an alkaloid that occurs naturally in barley and other plants. It stimulates the central nervous system and promotes weight loss by enhancing metabolism.
Formula Delivery – Our exclusive time-release transdermal patch delivers this directly into the bloodstream over an 8-hour period. This time-release function allows one’s system to efficiently process and metabolize all of the formula’s nutrient dosage.











Monday, August 24, 2015

AgeForce Weight Loss Patch Experiment - Holding steady at 4 pounds lost and 2 inches in waist circumference





Eight weeks so far I have lost 4 pounds and 2 inches off of my waist. I have to admit to not being the ideal candidate for this experiment due to my lack of being a non dieter. Or maybe I am ideal.

This will be my last week on the patch. I could be disappointed with pounds lost but I am not. Why? Because of the inches lost.


A few basic starting measurements as listed below:

Weight: 222 lbs
Body Fat: 41%
Waist Circumference: 44 inches.
Start Date: 7/6/15



Current measurement of progress.






The workout schedule is listed below in the link below.

My August Training - Century Sets - 100 rep workouts

 

I am amending my workout in that I am beginning a 30 minute jog per day cardio workout. Similar to the below link.

5K run: 7-week training schedule for beginners - Mayo Clinic



Wish me luck!




The Below Information is from the AgeForce Website:

Formula (Per Patch) Upgraded June 2015
  • EGCG 5mg – From green tea extract is the best-researched anti-inflammatory fat loss adjuvant your money can buy. In its purest form it will fire up your fat metabolism and help normalize your glucose levels.
  • Berberine HCL 10mg – A powerful fat-metabolic enhancer that acts similar to the potent diabetes drug metformin. Just like the prescription medication it acts mainly via an enzyme that's called AMPK. AMPK controls the glucose uptake and fatty acid oxidation in your cells and berberine ramps up both of them. Studies have also shown that berberine can reduce the levels of triglycerides and bad LDL cholesterol in your blood, albeit without any of the nasty side effects of prescription drugs with the same effects.
  • 3.5 Diiodothyronine (T2) 1mg – is a downstream metabolite that is a thermogenic activator that promotes the burning of body fat. 3.5 is also the most powerful and effective of the two forms of T2.
  • 7-Keto DHEA 20mg– (7-OXO DHEA) is a naturally occurring metabolite of DHEA that cannot convert to estrogen, testosterone or any downstream sex hormone making it a much safer choice for those wanting the well-known weight loss benefits of DHEA. Clinical trials and peer review studies show that 7-Keto DHEA works as a thermo genic that increases metabolic function and thus causes an increase in energy expenditure. This leads to greater calorie utilization with resulting fat loss. 7-Keto DHEA can also accelerate fat loss is through a reduction of cortisol production which place a roll in the storage of new body fat. So 7-Keto DHEA works two ways, by increasing body fat loss and inhibiting new fat storage.
  • Tyr-Somatostatin 5mg - is an advanced peptide that burns body fat without any of the negative effects of so-called “fat-burners” like caffeine, ephedrine, or guarana, that are used in other over-the-counter weight loss supplements and diet pills. Tyr-Somatostatin does not suppress natural thyroid production.
  • R Alpha Lipoic Acid (RLA) 5mg - is a great antioxidant. It is used in the body to break down carbohydrates, and to make energy. It also restores natural levels of vitamin C and vitamin E.
  • Hoodia 15mg – This is a safe and wonderful appetite suppressant. It doesn’t work when taken orally, but when delivered directly to the bloodstream via our patches, it will suppress appetite and those cravings that make it so hard to eat sensibly.
  • Yohimbine 10mg – Increases lipolysis as shown in multiple studies, especially during and following exercise, thus promoting safe, natural weight loss. Yohimbine is a mild stimulant.
  • Hordenine 4mg – Is an alkaloid that occurs naturally in barley and other plants. It stimulates the central nervous system and promotes weight loss by enhancing metabolism.
Formula Delivery – Our exclusive time-release transdermal patch delivers this directly into the bloodstream over an 8-hour period. This time-release function allows one’s system to efficiently process and metabolize all of the formula’s nutrient dosage.