SAMe has a wide range of benefits, including promotion of joint health, liver health, proper metabolism, fibromyalgia support, osteoarthritis support and mental function. SAMe is also used as a effective natural antidepressant.
For fibromyalgia: 400 mg. twice daily
For osteoarthritis: 600 mg, twice daily. or 400 mg. three times daily
For depression: 800 mg. twice daily
Source Citation (MLA 7th Edition)
Nutrition, Better. "Super SAMe: this powerful supplement relieves depression, fibromyalgia, and more." Better Nutrition May 2013: 18+.
Stoppani, Jim. "The Encyclopedia of Supplements A-F." Flex Dec. 2011: 196+.