Monday, July 1, 2013

5-Methyl-7-Methoxyisoflavone the Hardgainers Friend


5-Methyl-7-Methoxyisoflavone is a non-hormonal anabolic / anti-catabolic compound that has been shown to increase protein synthesis.

In addition, it helps preserve bone strength and muscle tendon integrity.

You will benefit from it's ability to improve recovery from your insane workouts.

Stack with Ipriflavone and Ecdysterone

Other Information:

Clayton's Health Facts: Methoxyisoflavone.

Effects of Methoxyisoflavone, Ecdysterone, and Sulfo ...

Animal Natural Anabolics
A Legit Alternative?

•Abidov M, Crendal F, Grachev S, Seifulla R, Ziegenfuss T. Effect of extracts from Rhodiola rosea and Rhodiola crenulata roots on ATP content in mitochondria of skeletal muscles. Institute of Immunopathology, Russian Academy of Natural Sciences, Moscow.
Bull Exp Biol Med. 2003 Dec;136(6):585-7. PMID: 15500079
•Anthony JC, Reiter AK, Anthony TG, Crozier SJ, Lang CH, MacLean DA, Kimball SR, and Jefferson LS. Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation. Diabetes 51: 928-936, 2002.
•Anthony JC, Lang CH, Crozier SJ, Anthony TG, MacLean DA, Kimball SR, and Jefferson LS. Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine. Am J Physiol Endocrinol Metab 282: E1092–E1101, 2002.
•Anthony JC, Reiter AK, Anthony TG, Crozier SJ, Lang CH, MacLean DA, Kimball SR, and Jefferson LS. Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation. Diabetes 51: 928–936, 2002.
•Baranov VB. The response of cardiovascular system to dosed physical load under the effect of herbal adaptogen. Contract 93-11-615 Phase I and Phase II. Moscow: Russian Federation Ministry of Health Institute of Medical and Biological Problems; 1994.
•Bidzinska B, et al. Effect of different chronic intermittent stressors and acetyl-l-carnitine on hypothalamic beta-endorphin and GnRH and on plasma testosterone levels in male rats. Neuroendocrinology 57:985-90, 1993.
•Bratusch-Marrain, et al. The influence of amino acids and somatostatin on prolactin and growth hormone release in man. Acta Endocrinol 90:403, 1979.
•Brodie A. Aromatase and its inhibitors: an overview. J Steroid Biochem 40(1-3):255, 1991.
•Campbell DR, Kurzer MS. Flavonoid inhibition of aromatase enzyme activity in human preadipocytes. J Steroid Biochem Mol Biol 46:381-388, 1993.
•Chermnykh NS, et al. The action of metandrostenolone and ecdysterones on the physical endurance of animals and on protein metabolism in the skeletal muscles. Farmocol Toksikol 1988;51:57-60.
•Dinan L. 2001, Phytoecdysteroids: biological aspects. Phytochemistry 57:325-339
•DiSilverio F, et al. Evidence that serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992; 21:309.
•Gadzhieva RM, et al. A comparative study of the anabolic action of ecdysten, leveton and Prime Plus, preparations of plant origin. Eksp Klin Faramkol 1995;58:46-8.
•Germia E. Antioxidant actions of acetyl-l-carnitine: in vitro study. Med Sci Res 16:699-700, 1988.
•Hammarqvist F, et al. Alpha-ketoglutarate preserves protein synthesis and free glutamine in skeletal muscle after surgery. Surgery 109(1):28-36, 1991.
•Karlsson HK, Nilsson PA, Nilsson J, Chibalin AV, Zierath JR, and Blomstrand E. Branched-chain amino acids increase p70S6K phosphorylation in human skeletal muscle after resistance exercise. Am J Physiol Endocrinol Metab 287: E1–E7, 2004
•Laszlo F, et al. Metabolic 5-methyl-isoflavone-derivatives, process for the preparation thereof and compositions containing the same. US Patent 4,163,746, August 7, 1979.
•Mamatkhanov A. U. et al. Isolation of Turkesterone from the epigeal part of ajuga turkestanica and it’s anabolic activity. Chemistry of natural compounds, 1998, vol. 34, pp. 150-154
•Nair KS, Schwartz RG, and Welle S. Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans. Am J Physiol Endocrinol Metab 263: E928–E934, 1992
•Norton LE, Layman DK. Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. J Nutrition. 2006 Feb;136(2):533S-537S.
•Otaka T, Okui S, Uchiyama M 1969, Stimulation of protein synthesis in mouse liver by ecdysone. Chemical & Pharmaceutical Bulletin (Japan) 17(1):75-81.
•RenĂ© Koopman, et al. Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects. Am J Physiol Endocrinol Metab 288: E645-E653, 2005.
•Sershon H, et al. Effect of acetyl-l-carnitine on the dopaminergic systems in aging animals. J Neurosci 30:555-59, 1991.
•Spasov AA, et al. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine 2000;7(2):85-9.
•Syrov VN, et al. Anabolic activity of phytoecdysone-ecdysterone isolated from Rhaponticum carhamoides (Willd.). Farmocol Toksikol 1976;39:690-3.
•Taglialagela G, et al. Acetyl-l-carnitine enhances the response of pc12 cells to nerve growth factor. Brain Res Dev Brain Res 59:221-30, 1991.