Wednesday, April 23, 2014

SuppVersity - Nutrition and Exercise Science for Everyone: Ask Dr. Andro: Are Colostrum and Milk Products in ...


SuppVersity - Nutrition and Exercise Science for Everyone: Ask Dr. Andro: Are Colostrum and Milk Products in ...: Image 1: Colostrum and other milk products Milky muscle builders or murky allergens? (image from SportRevue 6/2010) Question from Pet...

Physiological Effect / Classification Compound(s)
Opioid agonists (decrease gastric mobility, increase electrolyte and amino acid uptake) α- ,β-caseins, α-lactalbumin, β-lactoglobulin, serum albumin
ACE inhibitors (increase blood flow to intestinal epithelium) α- ,β-caseins
Mineral binding (increase absorption) α- ,β-caseins
Immunomodulators (increase immune response and phagocytic activity) α- ,β-caseins, gG, IgA, lactoferrin, glycolipids, oligosaccharides, prolactin, cytokines
Antimicrobial αs1 and s2-casein, lactoferrin, oligosaccharides, prolactin
Antithrombotic κ-casein
Probiotic κ-casein, lactoferrin, oligosaccharides
Opioid antagonist κ-casein, lactoferrin
Organ development and function IGF-1, TGF-α, EGF, TGF-β
Increase calcium metabolism and uptake Parathromone - P
Table 1: Milk as a "functional food". Physiological effects and their respective triggers.
(adapted from Schanbacher. 1998; Meisel. 1998 and Clare. 2000)
Author(s) Result(s)
Ferguson-Stegall. 2011b "CM [chocolate milk] postexercise improves aerobic power and body composition more effectively than CHO [carbohydrate] alone"
Ferguson-Stegall. 2011a "CM supplementation can improve subsequent exercise performance and provide a greater intracellular signaling stimulus for PRO synthesis compared to CHO and placebo"
Gilson. 2010 "CM provided similar muscle recovery responses to an isocaloric CHO beverage during four-days of ITD [increased training duration]. Future studies should investigate if the attenuated CK [creatine kinase = marker of muscle damage] levels observed with CM have functional significance during more demanding periods of training"
Pritchett. 2009 "These findings indicate no difference between CHOC and this commercial beverage as potential recovery aids for cyclists between intense workouts."
Thomas. 2009 "Participants cycled 51% and 43% longer after ingesting CM (32 +/- 11 min) than after ingesting [commercially available] CR [carbohydrate drink] (21 +/- 8 min) or FR [fluid replacement drink] (23 +/- 8 min)"
Carp. 2006 "[...] chocolate milk is an effective recovery aid between two exhausting exercise bouts"
Table 2: A selection of recent studies on the ergogenic effects of (chocolate-)milk

Author(s) Result(s)
Shing. 2006 "[10g/day] bovine CPC [colostrum concentrate] supplementation elicited improvements in TT40 [40 km time trial] performance during an HIT period and maintained ventilatory threshold following five consecutive days of HIT"
Buckley. 2003 same increase in peak power for 60g colostrum as with whey protein; no increase in IGF1
Brinkworth. 2004a "[cross sectional area of biceps increased more in trainees supplemented with 60g bovine colostrum than in whey control, but that was] due principally to a greater increase in skin and subcutaneous fat (SSF) CSA"
Buckley. 2003 same increase in peak power for 60g colostrum as with whey protein; no increase in IGF1
Buckley. 2002b "[...] latively few scientifically controlled studies have been conducted. The limited evidence that is currently available suggests that BC supplementation can increase lean body mass and improve exercise performance and recovery for a number of athletic activities, but an understanding of the mechanism by which this supplement exerts these effects remains elusive"
Buckley. 2002a "[...] supplementation with intact powder did not increase plasma IGF-I concentrations or improve performance during an initial bout of incremental running to exhaustion in our sample. However, performance during a second bout of exercise may be improved by as much as 5.2% in the average subject after 8 weeks of supplementation, possibly due to an enhancement of recovery"
Coombes. 2002 "Oral bovine colostrum supplementation at 20 g or 60 g/d provided a small but significant improvement in time trial performance in cyclists after a 2-h ride at 65% VO2max." [improvements were 20g colostrum+40g whey 60g+ colostrum 60g+ whey]
Antonio. 2001 "[...]supplementation with bovine colostrum (20 g/d) in combination with exercise training for 8 wk may increase bone-free lean body mass [+1.5 kg, while whey-placebo group increased overall BM by +2 kg] in active men and women."
Mero. 1997 "appears that a bovine colostrum supplement (Bioenervi) may increase serum IGF-I concentration in athletes during strength and speed training" (cf. discussion in the text)
Table 2: A selection of studies on the ergogenic effects of colostrum





  1. colostrum (skimmed) contains roughly 19x more androgens and 213x more estrogens than whole milk
  2. for milk and colostrum the full fat variety tends to have generally higher levels of both androgens and estrogens - for colostrum, for example the fat fraction contains 10x androgens and 10x more estrogens than the skimmed variety, which is also used as a base for most powdered colostrum supplements
  3. in the case of milk, the ratio of androgens to estrogens (AE-ratio) drops by -34% during the skimming process; in fact, skimmed milk contains more estradiol (per liter) than whole milk.
An Overdue Preliminary Conclusion
Will milk and/or colostrum kill you? No.

Will milk and/or colostrum make you look like Jay Cutler and
unbreakable like Bruce Willis aka David Dunn in the Y2K thriller Unbreakable
within days? Certainly not.

Well, I guess these are the two polar extremes of the preliminary conclusion to this "Ask Dr. Andro" segment and, as it is so often the case, the truth lies somewhere in between. I cannot
tell you your exact position on the death to ultimate health continuum as far as
your personal reaction to dairy consumption is concerned, I can only tell you
that even if your genetic polymorphisms allow you to consume dairy, the
chance that replacing your whey protein by a 6x more expensive colostrum powder
will make a beneficial difference in how you look, feel and perform are
minimal
.

I am not so sure however, if you would not see some, if only psychological (placebo) benefits if you mixed that whey into some real, i.e. whole, liquid and not powdered, 1st day colostrum you bought the very same day from your local farmer ;o)

That being said, I could certainly go on forever on milk, organic milk, milk from happy and milk from pasteur fed cows, the effects of soy on the milk you consume, raw milk, 1st day and 4th day
colostrum, and so on and so forth, but I suppose that Peter, who posed the original question (just in case you forgot due to the informational overkill of this not even half-done write-up), and the rest of you have enough to think about for the coming week. Ah... and in case you can't get enough of milk (I mean metaphorically) just pose another, hopefully more concrete "Ask Dr. Andro"
question
in the comment area or on the SuppVersity's facebook page ;-)


Nature gave you a strong immune defense network, but that system gets depleted as you age. Normal physical and mental stress can also wear down your defenses. Colostrum is the only supplement you can take to add back antibodies and action support in the bloodstream and also in the GI tract. It helps maintain a robust intestinal lining and promote healthy intestinal flora. Colostrum Plus supports muscle growth.

Colostrum provides over 100 beneficial components including several growth factors and cytokine precursors that you can't get from any other supplement to enhance stamina and support normal re-growth of lean muscle and tissue. Clinical studies show wide ranging health benefits for Colostrum including a significant increase in lean body mass and increases in anaerobic power, performance time, and sprint performance when compared to whey. Clinical studies also demonstrate the superiority of the ingredient in Symbiotics Colostrum Plus over other Colostrum sources.

Symbiotics guarantees per serving minimums of 1.5% Lactoferrin (14 mg), 25% Immunoglobulins (240 mg IG), and 3% Proline-Rich Polypeptides (29 mg PRP), Colostrum's most important component. Our unique Bio-lipid coating insures bioavailability. Without this protective layer, other Colostrums can be destroyed by stomach acids and offer limited benefit. We use only the first 2 milkings to guarantee potency and quality. Quality and Purity Guaranteed – We guarantee that this product meets the highest standards of quality, purity and freshness. Each bottle is safety sealed with an outer neckband. Do not use if neckband is broken or missing.

Nutrition Facts

Serving Size 1/3 Scoop
Servings Per Container 620
Amount Per Serving
Serving % DV
Colostrum Plus 960 mg -
*percent Daily Values are based on a 2,000 calorie diet.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Nutritions Facts are a simulation of the product "Nutrition Label". For the actual Nutrition Label please refer to the product packaging.

Directions

Mix 1/3 scoop twice daily with water or your drink of choice, on a empty stomach. (3 g scoop included). Triple this amount in times of environmental or physical stress. For children, cut these servings sizes in half. For athletic training and recovery purposes, it is safe to ingest up to 7 scoops (21 g) per day.

Warnings

Suitable for lactose-free diets. Contains milk. Close tightly and store in a dry place at room temperature.